Indopedia All Things Marijuana
Clinical endocannabinoid deficiency (CEDC) is a proposed spectrum disorder that has been implicated in a range of illnesses, including fibromyalgia, migraine and irritable bowel syndrome. So far, very little research has been conducted on this speculative disorder, but if it is found to exist, it could be responsible for these very common conditions as well as many related ones.
Migraine, serotonin and the blood plasma platelets
The three conditions feature common clinical and biochemical patterns that may point to underlying CEDC. Migraine is thought to be influenced by endocannabinoid function, as areas suspected to be involved with generation of migraines are also affected by cannabinoid activity; furthermore, the endocannabinoid anandamide, with its role in pain modulation and serotonin transmission, is believed to positively affect sufferers of the condition.
The biochemistry of migraine is highly complex and poorly understood, but it is…
