Researchers show chemical found naturally in cannabis may reduce anxiety-inducing effects of THC

A Johns Hopkins Medicine-led team has shown that d-limonene (left side of graphic), an essential oil derived from citrus—and found in cannabis—significantly reduces feelings of anxiety and panic, without altering the desired effect of THC (right side of graphic), the primary psychoactive ingredient of cannabis. Credit: M.E. Newman, Johns Hopkins Medicine, using public domain image

A Johns Hopkins Medicine-led research team has added to evidence that a chemical found naturally in cannabis (also known as marijuana) can—in the right amounts—lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive sister chemical found in cannabis. The finding has the potential to advance the medicinal use of THC and reduce the risks of its recreational use in some people.

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