Beyond that, though, it’s worth taking a good look at your long-term cannabis habits. “If you’re having a weed hangover, it’s a sign you’re not using cannabis optimally,” Dr. Sulak says. So, he recommends new users try using a dose that produces the most minimal (yet noticeable) effects for about three days before upping their consumption. And, for veteran users, he suggests abstaining from weed for two days before finding their minimal dose. Both of these protocols help your body build up a tolerance to the negative side effects of marijuana while also making you more sensitive to the positive effects, Dr. Sulak explains.