We're all familiar with the effects that come with nice hit of that sweet sticky icky, but many tokers are unaware about the actual role that the different chemicals in marijuana play in creating that high.

The Unknown Science Behind the “Entourage Effect” of Chemicals in Marijuana

We’re all familiar with the effects that come with nice hit of that sweet sticky icky, but many tokers are unaware about the actual role that the different chemicals in marijuana play in creating that high. As it turns out, so are most cannabis researchers. Most industry leaders like to imagine that different strains contain hundreds of compounds that produce a certain feeling for users, whether that be of energy, relaxation, or anything else in between.

The unique composition that different types of marijuana strains produce when smoked is widely known as the “entourage effect,” a fusion of hundreds of chemicals that include THC, cannabidiol, terpenes, and flavonoids. Some researchers believe that these compounds work together to enhance or alter the psychoactive and medicinal properties of cannabis. In theory, this effect is enabled when growers crossbreed different strains, producing personalized plants that could tackle the needs of every user. 

But the scientific validity on this so-called “entourage effect” is limited due to federal illegality, and some researchers are starting to doubt the impact of these different chemical combinations. Margaret Haney, a…

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