Know Your Medicine: CBG and CBGA

Experts report that there are at least 106 phytocannabinoids found in the trichomes of the cannabis flower. Most research has focused on the two most prominent “primary” cannabinoids, tetrahydrocannabinol (THC) and cannabidiol (CBD). However, many of the so-called “secondary” cannabinoids are responsible for adding to the therapeutic effects of cannabis as part of the entourage effect, the term used to describe how the many cannabinoid and terpenoid compounds in cannabis work synergistically to deliver beneficial effects.

Cannabinoid Biosynthesis Part 1 – CBG, THC, CBD, and CBC

Cannabigerol (CBG) and cannabigerolic acid (CBGA) are two of the many secondary phytocannabinoids found in the flower of the cannabis plant. The “A” in CBGA refers to the presence of a certain chemical structure called carboxylic acid.  CBG was initially isolated from hash by Israeli researchers in 1964, with subsequent research in Japan elucidating that CBGA was its precursor. CBG is one of the five most common cannabinoids along with THC, CBD, CBN (cannabinol) and CBC (cannabichromene). CBGA plays an extremely important role as the parent compound in the maturing cannabis flower…

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