Can cannabinoids help treat obsessive-compulsive disorder?

Credit: 2012, Mary Ann Liebert, Inc., publishers

The body’s endocannabinoid system, due to the critical role it plays in regulating neurotransmitter signaling, is an enticing target for drug development against disorders associated with anxiety, stress, and repetitive behaviors, such as obsessive-compulsive disorder (OCD). A comprehensive new review article that provides an overview of this complex system, endogenous and exogenous cannabinoids, results of animal studies and human trials to date, and recommendations for future directions is published in Cannabis and Cannabinoid Research.

The article entitled “The Endocannabinoid System: A New Treatment Target for Obsessive Compulsive Disorder?” was coauthored by Reilly Kayser, MD, Ivar Snorrasson, Ph.D., Margaret Haney, Ph.D., and H. Blair Simpson, MD, Ph.D., Columbia University Vagelos College of Physicians and Surgeons, and Francis Lee, MD, Ph.D., Weill Cornell Medical College, (New York, NY). The…

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