If you’re a cannabis nerd like we are, you might already be familiar with the Entourage Effect. An understanding of this essential cannabis concept helps us understand how different types of cannabis products create different experiences and effects.
Researchers have identified hundreds of compounds in cannabis. While we understand the primary effects of the most common compounds like THC and CBD, we have not yet been able to explain precisely how these components work together to produce different reactions. One common theory, the Entourage Effect, explains that some cannabis compounds that have minimal or no effect in isolation may generate significant effects when combined with additional cannabinoids and terpenes. Put simply, the beneficial impact of the whole plant is greater than the sum of its individual parts.
This may explain why whole plant cannabis is reported be so effective in treating certain medical conditions, while synthetically derived formulations of isolated THC or CBD often achieve less consistently positive patient outcomes. Researchers have explored the concept of synergy in herbal medicine for millennia. The idea that combining two or more…